Side Effects and What to do About Them

What is flushing?

Niacin sometimes causes redness, warmth, itching, and/or a tingling sensation on the face, neck, chest and back. This is called "flushing". This is a natural reaction signalling that niacin is in the bloodstream.

Most patients on ADVICOR will experience this sensation, usually at the start of therapy or when the dosing is increased. For most patients, the flushing occurs over the first 8 weeks of therapy and will become milder and less frequent as your body adjusts to ADVICOR.

If flushing occurs, it usually does so within 2 to 4 hours after taking ADVICOR and may last for a few hours.

In some patients, flushing may be more intense. Additional symptoms, such as rapid or pronounced heartbeat or dizziness, shortness of breath, sweating, chills, and/or swelling may occur; on rare occasions, fainting may occur. If the flushing wakes you up and you wish to get out of bed, take your time and get up slowly – especially if you start to feel faint or dizzy, or if you take blood pressure medication.

Other important reactions to be aware of:

• Fever
• Blurred vision
• If you are diabetic, inform your doctor if you notice any changes in your blood sugar.
• You should inform your doctor immediately and stop taking ADVICOR if you experience any signs of muscle pain, tenderness or weakness as well as generalized weakness and/or brownish or discoloured urine, as these may be signs of a rare but serious adverse drug reaction.

Other than flushing, the side effects most often seen are gastrointestinal in nature, such as stomach upset, constipation, gas, nausea and diarrhea. Rash, itching, pain in the abdomen, headache and dizziness are also occasionally observed.

Most side effects generally do not require medical attention and may come and go during treatment. But if any effect persists or becomes troublesome, talk with your doctor or pharmacist right away.

HOW TO STORE IT >